Retrospective

Secondary analysis of Fluids and Catheters Treatment Trial (FACTT) data reveal poor clinical outcomes in acute respiratory distress syndrome patients with diabetes.

Citation
Alanazi AH, Almuntashiri S, Sikora A, Zhang D, Somanath PR. Secondary analysis of Fluids and Catheters Treatment Trial (FACTT) data reveal poor clinical outcomes in acute respiratory distress syndrome patients with diabetes. Respir Med. 2024 Mar;223:107540. doi: 10.1016/j.rmed.2024.107540. Epub 2024 Jan 28. PMID: 38290602; PMCID: PMC10985622.
Principal Investigator
Sikora, Andrea
Project Name
Machine Learning Validation of Medication Regimen Complexity for Critical Care Pharmacist Resource Prediction

Hospitalization as an opportunity to improve lung cancer screening in high-risk patients.

Citation
Nielsen EM, Zhang J, Marsden J, Bays C, Moran WP, Mauldin PD, Lenert LA, Toll BA, Schreiner AD, Heincelman M. Hospitalization as an opportunity to improve lung cancer screening in high-risk patients. Cancer Epidemiol. 2024 Jun;90:102553. doi: 10.1016/j.canep.2024.102553. Epub 2024 Mar 8. PMID: 38460398.
Principal Investigator
Lenert, Leslie A.
Rheingold, Alyssa Ann
Project Name
EHR-based Screening and Intervention for Intimate Partner Violence

Implementation of a dedicated intake team reduces time to massed PTSD treatment.

Citation
Coleman JA, Werner B, Klassen BJ, Smith DL, Banerjee U, Held P. Implementation of a dedicated intake team reduces time to massed PTSD treatment. J Behav Health Serv Res. 2025 Apr;52(2):342-356. doi: 10.1007/s11414-024-09920-4. Epub 2024 Dec 17. Erratum in: J Behav Health Serv Res. 2025 Apr;52(2):371-372. doi: 10.1007/s11414-025-09931-9. PMID: 39690392; PMCID: PMC11997005.
Principal Investigator
Held, Philip
Thompson, Hale M.
Project Name
A Machine Learning Health System to Integrate Care for Substance Misuse and HIV Treatment and Prevention Among Hospitalized Patients

Unsupervised machine learning analysis to identify patterns of ICU medication use for fluid overload prediction.

Citation
Henry K, Deng S, Chen X, Zhang T, Devlin JW, Murphy DJ, Smith SE, Murray B, Kamaleswaran R, Most A, Sikora A; MRC‐ICU Investigator Team. Unsupervised machine learning analysis to identify patterns of ICU medication use for fluid overload prediction. Pharmacotherapy. 2025 Feb;45(2):76-86. doi: 10.1002/phar.4642. Epub 2025 Jan 3. PMID: 39749877; PMCID: PMC11834896.
Principal Investigator
Sikora, Andrea
Project Name
Artificial Intelligence-Based Health Information Technology Tools to Optimize Critical Care Pharmacist Resources Through Adverse Drug Event Prediction

Evaluation of influenza vaccine clinical decision support systems bundle for hospitalized children.

Citation
Kandaswamy S, Masterson E, Blanco R, Lantis P, Dawson TE, Ray E, Bryant C, Iyer S, Shane AL, Jernigan S, Orenstein EW. Evaluation of influenza vaccine clinical decision support systems bundle for hospitalized children. Hosp Pediatr. 2025 Apr 1;15(4):351-359. doi: 10.1542/hpeds.2024-008099. PMID: 40037515.
Principal Investigator
Orenstein, Evan William
Project Name
Improving Influenza Vaccine Uptake in Acute Care Settings

Mammographic classification of interval breast cancers and artificial intelligence performance.

Citation
Yu TT, Hoyt AC, Joines MM, Fischer CP, Yaghmai N, Chalfant JS, Chow L, Mortazavi S, Sears CD, Sayre J, Elmore JG, Hsu W, Milch HS. Mammographic classification of interval breast cancers and artificial intelligence performance. J Natl Cancer Inst. 2025 Aug 1;117(8):1627-1638. doi: 10.1093/jnci/djaf103. PMID: 40249223; PMCID: PMC12342771.
Principal Investigator
Hsu, William
Hoyt, Anne C
Project Name
Using Artificial Intelligence to Support Efficient Same-Day Diagnostic Imaging in Breast Cancer Screening

Impact of a clinical decision support system on CT pulmonary angiography yield and utilization in hospitalized patients.

Citation
Sharma A, Isabelle M, Hunsaker A, Dutta S, Lucier D, Rosovsky RP, Saini S, Landman A, Raja AS, Khorasani R, Lacson R. Impact of a clinical decision support system on CT pulmonary angiography yield and utilization in hospitalized patients. J Am Coll Radiol. 2025 Apr;22(4):449-460. doi: 10.1016/j.jacr.2024.11.030. Epub 2024 Dec 9. PMID: 39662713.
Principal Investigator
Lacson, Ronilda
Project Name
Clinical Decision Support for Disseminating and Implementing Patient-Centered Outcomes Research Clinical Evidence

External validation of an electronic phenotyping algorithm detecting attention to high body mass index in pediatric primary care.

Citation
Barron AG, Fenick AM, Maciejewski KR, Turer CB, Sharifi M. External validation of an electronic phenotyping algorithm detecting attention to high body mass index in pediatric primary care. Appl Clin Inform. 2024 Aug;15(4):700-708. doi: 10.1055/s-0044-1787975. Epub 2024 Aug 28. PMID: 39197473; PMCID: PMC11387092.
Principal Investigator
Sharifi, Mahnoos H.
Project Name
Using Electronic Health Records to Support Decision-Making in Pediatric Obesity Care