Clinical Decision Support System

Just another tool in their repertoire: Uncovering insights into public and patient perspectives on clinicians' use of machine learning in perioperative care.

Citation
Gonzalez XT, Steger-May K, Abraham J. Just another tool in their repertoire: Uncovering insights into public and patient perspectives on clinicians' use of machine learning in perioperative care. J Am Med Inform Assoc. 2025 Jan 1;32(1):150-162. doi: 10.1093/jamia/ocae257. PMID: 39401245; PMCID: PMC11648718.
Principal Investigator
Abraham, Joanna
Project Name
EnhanCed HandOffs (ECHO)

User-centered redesign of a clinical decision support system for pneumonia in the emergency department.

Citation
Christensen MA, Beebe R, Chen A, Reale C, Faiman J, Wrenn JO, Gradwohl SC, Slagle JM, Weitkamp AO, Nance BA, Kuttler KG, Carr JR, Peltan ID, Brown SM, Dean NC, Anders S, Ward MJ. User-centered redesign of a clinical decision support system for pneumonia in the emergency department. Appl Clin Inform. 2026 Jan;17(1):89-98. doi: 10.1055/a-2808-9190. Epub 2026 Feb 27. PMID: 41760359; PMCID: PMC12948636.
Principal Investigator
Dean, Nathan C.
Langlotz, Curtis P.
Ward, Michael J.
Project Name
Development of SMART on FHIR Interoperable Clinical Decision Support for Emergency Department Patients with Pneumonia and Pilot Deployment into Novel Epic Electronic Health Record Environments

Usability of a human factors-based clinical decision support in the emergency department: Lessons learned for design and implementation.

Citation
Salwei ME, Hoonakker P, Carayon P, Wiegmann D, Pulia M, Patterson BW. Usability of a Human Factors-based Clinical Decision Support in the Emergency Department: Lessons Learned for Design and Implementation. Hum Factors. 2024 Mar;66(3):647-657. doi: 10.1177/00187208221078625. Epub 2022 Apr 14. PMID: 35420923; PMCID: PMC9581441.
Principal Investigator
Carayon, Pascale
Project Name
Health Information Technology-Supported Process for Preventing and Managing Venous Thromboembolism

Implementation, Adoption, and Scaling Workgroup: Text message-facilitated PC CDS implementation: Key considerations and promising practices [internet].

Citation
Heaney-Huls K, Kawamoto K, Lobach DF, Jiménez F, Ryan S, Desai PJ; CDSiC Implementation, Adoption, and Scaling Workgroup; Dullabh PM. Implementation, Adoption, and Scaling Workgroup: Text message-facilitated PC CDS implementation: Key considerations and promising practices [internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2025 Aug. PMID: 40991752.
Project Name
Clinical Decision Support Innovation Collaborative (CDSiC)

Development of a patient-facing clinical decision support application for hypertension.

Citation
Bobo M, Canfield SM, Shaffer V, Storer M, Michaels L, Yates A, Rolbiecki AJ, Koopman R, Dorr D. Development of a patient-facing clinical decision support application for hypertension. Appl Clin Inform. 2025 Aug;16(4):1298-1309. doi: 10.1055/a-2697-2107. Epub 2025 Sep 8. PMID: 40921196; PMCID: PMC12507491.
Principal Investigator
Dorr, David
Koopman, Richelle J.
Project Name
Collaboration-Oriented Approach to Controlling High Blood Pressure (COACH)

Development of a patient-facing clinical decision support application for hypertension.

Citation
Bobo M, Canfield SM, Shaffer V, Storer M, Michaels L, Yates A, Rolbiecki AJ, Koopman R, Dorr D. Development of a patient-facing clinical decision support application for hypertension. Appl Clin Inform. 2025 Aug;16(4):1298-1309. doi: 10.1055/a-2697-2107. Epub 2025 Sep 8. PMID: 40921196; PMCID: PMC12507491.
Principal Investigator
Dorr, David
Project Name
Translating Hypertension Guidelines into Practice: Development of Interoperable Clinical Decision Support

Large language models management of complex medication regimens: A case-based evaluation.

Citation
Chase A, Most A, Xu S, Barreto E, Murray B, Henry K, Smith S, Hedrick T, Chen X, Li S, Liu T, Sikora A. Large language models management of complex medication regimens: A case-based evaluation. Front Pharmacol. 2025 Nov 24;16:1514445. doi: 10.3389/fphar.2025.1514445. PMID: 41368579; PMCID: PMC12682882.
Principal Investigator
Sikora, Andrea
Project Name
Machine Learning Validation of Medication Regimen Complexity for Critical Care Pharmacist Resource Prediction

Large language models management of complex medication regimens: A case-based evaluation.

Citation
Chase A, Most A, Xu S, Barreto E, Murray B, Henry K, Smith S, Hedrick T, Chen X, Li S, Liu T, Sikora A. Large language models management of complex medication regimens: A case-based evaluation. Front Pharmacol. 2025 Nov 24;16:1514445. doi: 10.3389/fphar.2025.1514445. PMID: 41368579; PMCID: PMC12682882.
Principal Investigator
Sikora, Andrea
Project Name
Artificial Intelligence-Based Health Information Technology Tools to Optimize Critical Care Pharmacist Resources Through Adverse Drug Event Prediction

Shared decision making using digital twins in knee osteoarthritis care: A randomized clinical trial of an AI-enabled decision aid versus education alone on decision quality, physical function, and user experience.

Citation
Jayakumar P, Rathouz PJ, Lin E, Trutner Z, Uhler LM, Andrawis J, Koenig KM, Tsevat J, Bozic KJ. Shared decision making using digital twins in knee osteoarthritis care: A randomized clinical trial of an AI-enabled decision aid versus education alone on decision quality, physical function, and user experience. EClinicalMedicine. 2025 Oct 4;89:103545. doi: 10.1016/j.eclinm.2025.103545. PMID: 41112505; PMCID: PMC12528923.
Principal Investigator
Bozic, Kevin John
Tsevat, Joel
Project Name
Incorporating Patient-Reported Outcomes into Shared Decision Making with Patients with Osteoarthritis of the Knee

Assessment of 3 standards-based clinical decision support (CDS) tools in an academic electronic health record using Clinical Quality Language, CDS Hooks, and Fast Healthcare Interoperability Resources: A retrospective evaluation.

Citation
Isabelle M, Ip IK, Bakhtin M, Schneider L, Raja AS, Dutta S, Landman A, Lacson R. Assessment of 3 standards-based clinical decision support (CDS) tools in an academic electronic health record using Clinical Quality Language, CDS Hooks, and Fast Healthcare Interoperability Resources: A retrospective evaluation. JAMIA Open. 2025 Jul 30;8(4):ooaf085. doi: 10.1093/jamiaopen/ooaf085. PMID: 40741009; PMCID: PMC12309839.
Principal Investigator
Lacson, Ronilda
Project Name
Clinical Decision Support for Disseminating and Implementing Patient-Centered Outcomes Research Clinical Evidence