Large Language Models

Lab-AI: Using retrieval augmentation to enhance language models for personalized lab test interpretation in clinical medicine.

Citation
Wang X, Ouyang H, Bhasuran B, Luo X, Hanna K, Lustria MLA, He Z. Lab-AI: Using retrieval augmentation to enhance language models for personalized lab test interpretation in clinical medicine. Proc (IEEE Int Conf Healthc Inform). 2025;2025:359-368. doi: 10.1109/ICHI64645.2025.00025. PMID: 41409767; PMCID: PMC12707499.
Principal Investigator
He, Zhe
Lustria, Mia Liza A.
Project Name
LabGenie: A Patient-Engagement Tool to Aid Older Adults' Understanding of Lab Test Results

Large language models management of complex medication regimens: A case-based evaluation.

Citation
Chase A, Most A, Xu S, Barreto E, Murray B, Henry K, Smith S, Hedrick T, Chen X, Li S, Liu T, Sikora A. Large language models management of complex medication regimens: A case-based evaluation. Front Pharmacol. 2025 Nov 24;16:1514445. doi: 10.3389/fphar.2025.1514445. PMID: 41368579; PMCID: PMC12682882.
Principal Investigator
Sikora, Andrea
Project Name
Machine Learning Validation of Medication Regimen Complexity for Critical Care Pharmacist Resource Prediction

Large language models management of complex medication regimens: A case-based evaluation.

Citation
Chase A, Most A, Xu S, Barreto E, Murray B, Henry K, Smith S, Hedrick T, Chen X, Li S, Liu T, Sikora A. Large language models management of complex medication regimens: A case-based evaluation. Front Pharmacol. 2025 Nov 24;16:1514445. doi: 10.3389/fphar.2025.1514445. PMID: 41368579; PMCID: PMC12682882.
Principal Investigator
Sikora, Andrea
Project Name
Artificial Intelligence-Based Health Information Technology Tools to Optimize Critical Care Pharmacist Resources Through Adverse Drug Event Prediction

PharmacyGPT: Exploration of artificial intelligence for medication management in the intensive care unit.

Citation
Liu Z, Xu S, Wu Z, Murray B, F Barreto E, Li S, Liu W, Li X, Liu T, Sikora A. PharmacyGPT: Exploration of artificial intelligence for medication management in the intensive care unit. BMC Med Inform Decis Mak. 2025 Oct 28;25(1):398. doi: 10.1186/s12911-025-03230-1. PMID: 41152866; PMCID: PMC12570815.
Principal Investigator
Sikora, Andrea
Project Name
Artificial Intelligence-Based Health Information Technology Tools to Optimize Critical Care Pharmacist Resources Through Adverse Drug Event Prediction

PharmacyGPT: Exploration of artificial intelligence for medication management in the intensive care unit.

Citation
Liu Z, Xu S, Wu Z, Murray B, F Barreto E, Li S, Liu W, Li X, Liu T, Sikora A. PharmacyGPT: Exploration of artificial intelligence for medication management in the intensive care unit. BMC Med Inform Decis Mak. 2025 Oct 28;25(1):398. doi: 10.1186/s12911-025-03230-1. PMID: 41152866; PMCID: PMC12570815.
Principal Investigator
Sikora, Andrea
Project Name
Machine Learning Validation of Medication Regimen Complexity for Critical Care Pharmacist Resource Prediction

The value of simulation testing for the evaluation of ambient digital scribes: A case report.

Citation
Biro JM, Handley JL, Mickler J, Reddy S, Kottamasu V, Ratwani RM, Cobb NK. The value of simulation testing for the evaluation of ambient digital scribes: A case report. J Am Med Inform Assoc. 2025 May 1;32(5):928-931. doi: 10.1093/jamia/ocaf052. PMID: 40116912; PMCID: PMC12012335.
Principal Investigator
Biro, Joshua
Project Name
Guiding the Safe and Effective Integration of Ambient Digital Scribes into Primary Care

Opportunities and risks of artificial intelligence in patient portal messaging in primary care.

Citation
Biro JM, Handley JL, Malcolm McCurry J, Visconti A, Weinfeld J, Gregory Trafton J, Ratwani RM. Opportunities and risks of artificial intelligence in patient portal messaging in primary care. NPJ Digit Med. 2025 Apr 24;8(1):222. doi: 10.1038/s41746-025-01586-2. PMID: 40275104; PMCID: PMC12022076.
Principal Investigator
Biro, Joshua
Project Name
Guiding the Safe and Effective Integration of Ambient Digital Scribes into Primary Care

Ontology enrichment using a large language model: Applying lexical, semantic, and knowledge network-based similarity for concept placement.

Citation
Kollapally NM, Geller J, Keloth VK, He Z, Xu J. Ontology enrichment using a large language model: Applying lexical, semantic, and knowledge network-based similarity for concept placement. J Biomed Inform. 2025 Aug;168:104865. doi: 10.1016/j.jbi.2025.104865. Epub 2025 Jun 19. PMID: 40543734.
Principal Investigator
He, Zhe
Lustria, Mia Liza A.
Project Name
LabGenie: A Patient-Engagement Tool to Aid Older Adults' Understanding of Lab Test Results

Quality of answers of generative large language models versus peer users for interpreting laboratory test results for lay patients: Evaluation study.

Citation
He Z, Bhasuran B, Jin Q, Tian S, Hanna K, Shavor C, Arguello LG, Murray P, Lu Z. Quality of answers of generative large language models versus peer users for interpreting laboratory test results for lay patients: Evaluation study. J Med Internet Res. 2024 Apr 17;26:e56655. doi: 10.2196/56655. PMID: 38630520; PMCID: PMC11063893.
Principal Investigator
He, Zhe
Lustria, Mia Liza A.
Project Name
LabGenie: A Patient-Engagement Tool to Aid Older Adults' Understanding of Lab Test Results