Machine Learning

Just another tool in their repertoire: Uncovering insights into public and patient perspectives on clinicians' use of machine learning in perioperative care.

Citation
Gonzalez XT, Steger-May K, Abraham J. Just another tool in their repertoire: Uncovering insights into public and patient perspectives on clinicians' use of machine learning in perioperative care. J Am Med Inform Assoc. 2025 Jan 1;32(1):150-162. doi: 10.1093/jamia/ocae257. PMID: 39401245; PMCID: PMC11648718.
Principal Investigator
Abraham, Joanna
Project Name
EnhanCed HandOffs (ECHO)

A randomized controlled trial of artificial intelligence-based analytics for clinical deterioration.

Citation
Keim-Malpass J, Ratcliffe SJ, Clark MT, Krahn KN, Monfredi OJ, Hamil S, Yousefvand G, Jones MK, Nelson A, Moorman LP, Moorman JR, Bourque JM. A randomized controlled trial of artificial intelligence-based analytics for clinical deterioration. Sci Rep. 2026 Feb 5;16(1):7345. doi: 10.1038/s41598-026-39051-z. PMID: 41644641; PMCID: PMC12923516.
Principal Investigator
Keim-Malpass, Jessica
Bourque, Jamieson MacDonald
Project Name
Predictive Monitoring: IMPact of Real-Time Predictive Monitoring in Acute Care Cardiology Trial (PM-IMPACCT)

Machine learning-based prediction of prolonged duration of mechanical ventilation using medication data.

Citation
Murray B, Zhao B, Chen Z, Smith SE, Kong Y, Shen Y, Li S, Chen X, Sikora A; MRC‐ICU Investigator Team. Machine learning-based prediction of prolonged duration of mechanical ventilation using medication data. Pharmacotherapy. 2026 Feb;46(2):e70090. doi: 10.1002/phar.70090. Epub 2026 Jan 6. PMID: 41495589.
Principal Investigator
Sikora, Andrea
Project Name
Machine Learning Validation of Medication Regimen Complexity for Critical Care Pharmacist Resource Prediction

Machine learning-based prediction of prolonged duration of mechanical ventilation using medication data.

Citation
Murray B, Zhao B, Chen Z, Smith SE, Kong Y, Shen Y, Li S, Chen X, Sikora A; MRC‐ICU Investigator Team. Machine learning-based prediction of prolonged duration of mechanical ventilation using medication data. Pharmacotherapy. 2026 Feb;46(2):e70090. doi: 10.1002/phar.70090. Epub 2026 Jan 6. PMID: 41495589.
Principal Investigator
Sikora, Andrea
Project Name
Artificial Intelligence-Based Health Information Technology Tools to Optimize Critical Care Pharmacist Resources Through Adverse Drug Event Prediction

An artificial intelligence-based framework for predicting emergency department overcrowding: Development and evaluation study.

Citation
Vural O, Ozaydin B, Aram KY, Booth J, Lindsey BF, Ahmed A. An artificial intelligence-based framework for predicting emergency department overcrowding: Development and evaluation study. JMIR Med Inform. 2025 Sep 17;13:e73960. doi: 10.2196/73960. PMID: 40961493; PMCID: PMC12489414.
Principal Investigator
Ahmed, Abdulaziz
Ozaydin, Bunyamin
Project Name
Building and Implementing a Predictive Decision Support System Based on a Proactive Full Capacity Protocol to Mitigate Emergency Department Overcrowding Problems

Prediction of pharmacist medication interventions using medication regimen complexity.

Citation
Zhao B, Shen Y, Devlin JW, Murphy DJ, Smith SE, Murray B, Rowe S, Sikora A. Prediction of pharmacist medication interventions using medication regimen complexity. JAMIA Open. 2025 Nov 3;8(6):ooaf138. doi: 10.1093/jamiaopen/ooaf138. PMID: 41190317; PMCID: PMC12582545.
Principal Investigator
Sikora, Andrea
Project Name
Artificial Intelligence-Based Health Information Technology Tools to Optimize Critical Care Pharmacist Resources Through Adverse Drug Event Prediction

Prediction of pharmacist medication interventions using medication regimen complexity.

Citation
Zhao B, Shen Y, Devlin JW, Murphy DJ, Smith SE, Murray B, Rowe S, Sikora A. Prediction of pharmacist medication interventions using medication regimen complexity. JAMIA Open. 2025 Nov 3;8(6):ooaf138. doi: 10.1093/jamiaopen/ooaf138. PMID: 41190317; PMCID: PMC12582545.
Principal Investigator
Sikora, Andrea
Project Name
Machine Learning Validation of Medication Regimen Complexity for Critical Care Pharmacist Resource Prediction

Comparing the performance of screening surveys versus predictive models in identifying patients in need of health-related social need services in the emergency department.

Citation
Mazurenko O, Hirsh AT, Harle CA, Shen J, McNamee C, Vest JR. Comparing the performance of screening surveys versus predictive models in identifying patients in need of health-related social need services in the emergency department. PLoS One. 2024 Nov 20;19(11):e0312193. doi: 10.1371/journal.pone.0312193. PMID: 39565746; PMCID: PMC11578524.
Principal Investigator
Vest, Joshua Ryan
Project Name
Predictive Modeling for Social Needs in Emergency Department Settings

Mitigating racial bias in machine learning.

Citation
Kostick-Quenet KM, Cohen IG, Gerke S, Lo B, Antaki J, Movahedi F, Njah H, Schoen L, Estep JE, Blumenthal-Barby JS. Mitigating racial bias in machine learning. J Law Med Ethics. 2022;50(1):92-100. doi: 10.1017/jme.2022.13. PMID: 35243993; PMCID: PMC12140104.
Principal Investigator
Blumenthal-Barby, Jennifer
Project Name
A Multi-Site Trial to Test Benefits of Adding a Personalized Risk Calculator to an Online Decision Aid for Left Ventricular Assist Device